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mirsoglasnomne


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Как получить ребёнка c большим инбридингом, чем от брата и сестры?
mirsoglasnomne
6 поколений должны состоять из 62 разных людей. У Карла II Габсбурга, короля Испании, из 32. 8 поколений должны состоять из 254 разных людей. У Карла II из 82.
Анна Австрийская (1528–90) приходилась Карлу (1661 – 1700): great-great-aunt, great-great-great-aunt, great-great-great-grandmother and great-great-great-great-grandmother twice.
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For the child of a brother and sister, one quarter of their total genomes, on average, of all their genes will be the same on both of the pairs of chromosomes, one to twenty-three. The chances that some of these will be alleles that are recessively dangerous is high. The measure is called an inbreeding coefficient, given the letter F, and the child of a brother and sister will have an F value of 0.25.

In 2009, Gonzalo Alvarez and his team of Spanish geneticists went back sixteen generations from Charles II, and incorporated more than 3,000 individuals to calculate his F value. It came out as 0.254. Charles, through generation after generation of uncle–niece pairings or first cousin pairings, was more cumulatively inbred that the child of a brother and sister.

Rutherford, Adam. “A Brief History of Everyone who Ever Lived: The Stories in Our Genes.” Orion, 2016

Posts from This Journal by “biology” Tag


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Из математики известно, что сумма первых n членов ряда a(n)=2↑n равна 2↑(n+1)-1.
Таким образом, 6 поколений (от нулевого до пятого) должны состоять из 63 разных людей, 8 поколений (от нулевого до седьмого) должны состоять из 255 разных людей.

Edited at 2017-03-03 12:26 pm (UTC)

Наверное, автор не посчитал везде самого Карла

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